Brian Samuel Epstein (19 September 1934 – 27 August 1967) was an English music entrepreneur, and the manager of The Beatles. He also managed several other musical artists such as Gerry & the Pacemakers, Billy J. Kramer and the Dakotas, Cilla Black, The Remo Four & The Cyrkle. His management company was named NEMS Enterprises, after his family's music stores, called NEMS (North End Music Stores).

Epstein paid for The Beatles to record a demo in Decca's studios, which Epstein later persuaded George Martin to listen to, as Decca was not interested in signing the band. Epstein was then offered a contract by Martin on behalf of EMI's small Parlophone label, even though they had previously been rejected by almost every other British record company. Martin later explained that Epstein's enthusiasm and his confidence that The Beatles would one day become internationally famous convinced him to sign them.

 The Beatles' early success has been attributed to Epstein's management and sense of style. Paul McCartney said of Epstein: "If anyone was the Fifth Beatle, it was Brian. Epstein wasn't only the Beatles manager, he was their most trusted friend and confidant, attending John Lennon's wedding to Cynthia in the role of "best man"

The Guesthouse was home to Brian Epsteins father Harry. Brian has often referred to his "Happy Days in Anfield Road". As does Liverpool's Cultural Ambassador, Joe Flannery who remembers this house from his youth. There is a relaxed and un-pretentious "feel" here and it is enjoyed by all.